Slippery Elm
Ulmus rubra · Ulmus fulva · Slippery elm bark
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Slippery elm (Ulmus rubra, Ulmus fulva) is the inner bark of a North American tree whose mucilage forms a viscous, soothing coat on mucosal surfaces1. It is used for minor cough and sore throat, for gastrointestinal complaints including irritable bowel syndrome, and topically for skin irritation1. It is also a popular remedy for heartburn and other esophageal symptoms. The typical patient is someone with throat or upper digestive irritation looking for a non-pharmacologic option.
Human research is limited to about three small trials, all of multi-ingredient products, in irritable bowel syndrome, digestive disorders, and healthy adults taking a detoxification blend. An open-label, uncontrolled pilot study of a slippery elm formula reported better bowel habit and symptoms in constipation-predominant irritable bowel syndrome. For cough and skin use, human data are lacking1. A 2021 case report described eosinophilic colitis potentially triggered by an Ulmus rubra-rich product6. Products listing slippery elm number over 1,200 in the NIH Dietary Supplement Label Database, mostly powders and capsules; see Form comparison.
LiverTox rates slippery elm as an unlikely cause of clinically apparent liver injury7. A US product label asks that medications be taken an hour before the product, and many labels direct pregnant or nursing users to consult a physician5.
Last updated October 16, 2026. Read how we make monographs.
In the full monograph
28 sources, 11 studies
- When to useThe situations practitioners use it for, each with the reason and the study behind it.
- SafetyWho should avoid it, who needs extra care, and the side effects reported in studies.
- InteractionsThe medicines and supplements it interacts with, the effect of each, and what labeling says to watch.
- Protocol notesThe doses used in studies, how and when they were taken, and how the forms on the market compare.
- How it worksWhat it is and how it works in the body, in plain terms.
- Published studiesThe studies behind each use, popular claims checked against them, and trials still under way.
- Word of mouthWhat patients and practitioners report online, kept separate from the clinical evidence.
- Clinical perspectiveA closing read of where the evidence is solid, where it is thin, and what has not been studied.
Sources
- 1MSKCCmskcc.orgMemorial Sloan Kettering — About Herbs, Botanicals & Other Products
- 2Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study.pubmed.ncbi.nlm.nih.govHawrelak, Myers · Journal of alternative and complementary medicine (New York, N.Y.) · 2010 · Pubmed
- 3Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders.pubmed.ncbi.nlm.nih.govRied, Travica, Dorairaj et al. · Nutrition research (New York, N.Y.) · 2020 · Pubmed
- 4Popular Remedies for Esophageal Symptoms: a Critical Appraisal.pubmed.ncbi.nlm.nih.govAhuja, Ahuja · Current gastroenterology reports · 2019 · Pubmed
- 5US product labelsdsld.od.nih.govWarnings printed on US dietary supplement labels with this ingredient, from the NIH Office of Dietary Supplements' Dietary Supplement Label Database (DSLD). Manufacturers' precautions, not evidence of harm
- 6Subserous Type of Eosinophilic Colitis: A Rare Disease.pubmed.ncbi.nlm.nih.govAmado, Silva Leal, Neto et al. · European journal of case reports in internal medicine · 2021 · Pubmed
- 7NIH LiverToxncbi.nlm.nih.govLiverTox, the National Institutes of Health review of liver injury caused by drugs and supplements, with its likelihood score (National Institute of Diabetes and Digestive and Kidney Diseases)