Fenugreek
Trigonella foenum-graecum · Fenugreek seed
Snapshot
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Fenugreek (Trigonella foenum-graecum) is a clover-like herb whose maple-scented seeds are used as a spice and a traditional medicine8. Seed fiber and saponins are thought to slow gut absorption of glucose and cholesterol10. One use is testosterone support in aging men: a specialised seed extract raised testosterone and eased age-related androgen symptoms in healthy men aged 43 to 703. It is also taken for perimenopausal symptoms, polycystic ovary syndrome5, lactation, and dysmenorrhea.
Meta-analyses of randomized trials found lower glycated hemoglobin, though trial quality and heterogeneity limit confidence1, 11, 12. They also found lower total and low-density lipoprotein cholesterol2, 11, 13. Standardized extracts raised testosterone in some trials of middle-aged and older men3, while lactation and dysmenorrhea trials are low-certainty. A 2026 network meta-analysis of randomized trials in metabolic dysfunction-associated steatotic liver disease ranked fenugreek favorably for liver fat endpoints, though the authors judged the overall evidence uncertain14. Products come as capsules, powders, teas, and liquids; see Form comparison.
The most consequential caution is pregnancy: amounts above those in food have been linked to birth defects in animals and people8. The European Medicines Agency traditional-use monograph advises close glycemic monitoring in patients treated for diabetes9, and Health Canada labels ask for a practitioner's advice before use in diabetes15.
Last updated October 16, 2026. Read how we make monographs.
In the full monograph
62 sources, 53 studies
- When to useThe situations practitioners use it for, each with the reason and the study behind it.
- SafetyWho should avoid it, who needs extra care, and the side effects reported in studies.
- InteractionsThe medicines and supplements it interacts with, the effect of each, and what labeling says to watch.
- Protocol notesThe doses used in studies, how and when they were taken, and how the forms on the market compare.
- How it worksWhat it is and how it works in the body, in plain terms.
- Published studiesThe studies behind each use, popular claims checked against them, and trials still under way.
- Word of mouthWhat patients and practitioners report online, kept separate from the clinical evidence.
- Clinical perspectiveA closing read of where the evidence is solid, where it is thin, and what has not been studied.
Sources
- 1Effect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials.pubmed.ncbi.nlm.nih.govNeelakantan, Narayanan, de Souza et al. · Nutrition journal · 2014 · Pubmed
- 2Effect of fenugreek consumption on serum lipid profile: A systematic review and meta-analysis.pubmed.ncbi.nlm.nih.govHeshmat-Ghahdarijani, Mashayekhiasl, Amerizadeh et al. · Phytotherapy research : PTR · 2020 · Pubmed
- 3Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study.pubmed.ncbi.nlm.nih.govRao, Steels, Inder et al. · The aging male : the official journal of the International Society for the Study of the Aging Male · 2016 · Pubmed
- 4Efficacy of a novel extract of fenugreek seeds in alleviating vasomotor symptoms and depression in perimenopausal women: A randomized, double-blinded, placebo-controlled study.pubmed.ncbi.nlm.nih.govKhanna, John, Das et al. · Journal of food biochemistry · 2020 · Pubmed
- 5Efficacy of a Proprietary Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst®) in Women with Polycystic Ovary Syndrome (PCOS): a Randomized, Double-Blind, Placebo-Controlled Study.pubmed.ncbi.nlm.nih.govSingh, Gainder, Banerjee et al. · Journal of the American Nutrition Association · 2023 · Pubmed
- 6Oral galactagogues (natural therapies or drugs) for increasing breast milk production in mothers of non-hospitalised term infants.pubmed.ncbi.nlm.nih.govFoong, Tan, Foong et al. · The Cochrane database of systematic reviews · 2020 · Pubmed
- 7Dietary supplements for dysmenorrhoea.pubmed.ncbi.nlm.nih.govPattanittum, Kunyanone, Brown et al. · The Cochrane database of systematic reviews · 2016 · Pubmed
- 8NCCIHnccih.nih.govNational Center for Complementary and Integrative Health
- 9EMAema.europa.euEuropean Medicines Agency — European Union herbal monograph from the Committee on Herbal Medicinal Products (HMPC)
- 10MSKCCmskcc.orgMemorial Sloan Kettering — About Herbs, Botanicals & Other Products
- 11The Effects of Fenugreek on Cardiometabolic Risk Factors in Adults: A Systematic Review and Meta-analysis.pubmed.ncbi.nlm.nih.govKhodamoradi, Khosropanah, Ayati et al. · Complementary therapies in medicine · 2020 · Pubmed
- 12Effect of Fenugreek on Hyperglycemia: A Systematic Review and Meta-Analysis.pubmed.ncbi.nlm.nih.govShabil, Bushi, Bodige et al. · Medicina (Kaunas, Lithuania) · 2023 · Pubmed
- 13Effect of fenugreek supplementation on blood lipids and body weight: A systematic review and meta-analysis of randomized controlled trials.pubmed.ncbi.nlm.nih.govAskarpour, Alami, Campbell et al. · Journal of ethnopharmacology · 2020 · Pubmed
- 14Efficacy of plant extracts for metabolic dysfunction-associated steatotic liver disease: a network meta-analysis.pubmed.ncbi.nlm.nih.govXie, Chen · Frontiers in pharmacology · 2026 · Pubmed
- 15Health Canadahealth-products.canada.caLabel statements and adult daily amounts Health Canada authorized on licensed natural health products with this ingredient alone, from the Licensed Natural Health Products Database. Contains information licensed under the Open Government Licence – Canada