Cordyceps
Cordyceps sinensis · Ophiocordyceps sinensis · Cordyceps militaris · Cordycepin · Dong Chong Xia Cao
Snapshot
| Indications | Contraindications |
|---|---|
Cordyceps names insect-parasitizing fungi, chiefly Ophiocordyceps sinensis and Cordyceps militaris, used in traditional Chinese medicine for fatigue, cough, and sexual dysfunction7. Its effects are attributed mainly to modulation of immune cell activity9. People take it for immune support, stamina, kidney function, and lung health, typically adults seeking stamina or immune support, or those with chronic respiratory or kidney disease7.
Healthy-adult trials found higher natural killer (NK) cell activity with Cordyceps preparations1, 2. Meta-analyses of Chinese trials found better lung function with Bailing capsule in stable chronic obstructive pulmonary disease (COPD) and better quality of life with adjuvant use in lung cancer. Kidney-protection evidence is low certainty6, and exercise performance results are mixed7. In mice with lipopolysaccharide-induced acute lung injury, a 2024 study found a Cordyceps militaris extract reduced lung inflammation; no human trial has tested it. Products listing Cordyceps are mostly capsules, powders, and liquid extracts; see Form comparison.
Memorial Sloan Kettering advises against use in myelogenous cancers because animal studies showed red blood cell progenitor proliferation7. Its patient page tells people taking insulin or warfarin to talk with their healthcare provider7.
Last updated October 16, 2026. Read how we make monographs.
In the full monograph
73 sources, 57 studies
- When to useThe situations practitioners use it for, each with the reason and the study behind it.
- SafetyWho should avoid it, who needs extra care, and the side effects reported in studies.
- InteractionsThe medicines and supplements it interacts with, the effect of each, and what labeling says to watch.
- Protocol notesThe doses used in studies, how and when they were taken, and how the forms on the market compare.
- How it worksWhat it is and how it works in the body, in plain terms.
- Published studiesThe studies behind each use, popular claims checked against them, and trials still under way.
- Word of mouthWhat patients and practitioners report online, kept separate from the clinical evidence.
- Clinical perspectiveA closing read of where the evidence is solid, where it is thin, and what has not been studied.
Sources
- 1Immunomodulatory effects of a mycelium extract of Cordyceps (Paecilomyces hepiali; CBG-CS-2): a randomized and double-blind clinical trial.pubmed.ncbi.nlm.nih.govJung, Jung, Choi et al. · BMC complementary and alternative medicine · 2019 · Pubmed
- 2A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults.pubmed.ncbi.nlm.nih.govOntawong, Pengnet, Thim-Uam et al. · Scientific reports · 2024 · Pubmed
- 3An Immunomodulatory Mushroom, Cordyceps militaris, and Its Constituents: A Review of In Vitro/In Vivo Studies and Clinical Trials.pubmed.ncbi.nlm.nih.govYang, Jin, Jiang et al. · Phytotherapy research : PTR · 2026 · Pubmed
- 4Therapeutic efficacy and pharmacological mechanism of Bailing capsule on chronic obstructive pulmonary disease: a meta-analysis and network pharmacology.pubmed.ncbi.nlm.nih.govMa, Jin · Pharmaceutical biology · 2024 · Pubmed
- 5Adjuvant treatment with Cordyceps sinensis for lung cancer: A systematic review and meta-analysis of randomized controlled trials.pubmed.ncbi.nlm.nih.govWang, Wang, Qi · Journal of ethnopharmacology · 2024 · Pubmed
- 6Fermented Ophiocordyceps sinensis mycelium products for preventing contrast-associated acute kidney injury: a systematic review of randomized controlled trials.pubmed.ncbi.nlm.nih.govPu, Li, Shen et al. · Renal failure · 2024 · Pubmed
- 7MSKCCmskcc.orgMemorial Sloan Kettering — About Herbs, Botanicals & Other Products
- 8US product labelsdsld.od.nih.govWarnings printed on US dietary supplement labels with this ingredient, from the NIH Office of Dietary Supplements' Dietary Supplement Label Database (DSLD). Manufacturers' precautions, not evidence of harm
- 9The Chemical Constituents and Pharmacological Actions of Cordyceps sinensis.pubmed.ncbi.nlm.nih.govLiu, Wang, Wang et al. · Evidence-based complementary and alternative medicine : eCAM · 2015 · Pubmed