Carob
Ceratonia siliqua · Carob fiber
Snapshot
| Indications | Contraindications |
|---|---|
Carob (Ceratonia siliqua) is the pod of a Mediterranean legume tree; carob fiber comes from the pulp and carob bean gum from the seed17. Tannin-rich pod powder is also used for acute diarrhea in children, carob for male infertility, and carob bean gum to thicken infant formula for regurgitation.
Carob-containing solid foods generally produced low-to-moderate postprandial glycemic responses in healthy adults, while insulin-sensitizing effects specific to carob remain preliminary4. A 2026 randomized trial in prediabetes found a liquid concentrate lowered glycated hemoglobin and glucose compared with placebo3. In infertile men, a 2026 meta-analysis of randomized trials and in vitro studies found carob supplementation improved sperm motility, and larger trials are still needed11. Among 1903 products listing carob, the sampled ones are mostly liquids and powders, with some tablets and capsules; see Form comparison.
Some United States (US) product labels warn against use in pregnancy and lactation without a practitioner's advice16. In a double-blind challenge, peanut-allergic children showed sensitization to raw carob in testing, yet neither raw nor cooked carob provoked clinical reactions18.
Last updated October 17, 2026. Read how we make monographs.
In the full monograph
58 sources, 47 studies
- When to useThe situations practitioners use it for, each with the reason and the study behind it.
- SafetyWho should avoid it, who needs extra care, and the side effects reported in studies.
- InteractionsThe medicines and supplements it interacts with, the effect of each, and what labeling says to watch.
- Protocol notesThe doses used in studies, how and when they were taken, and how the forms on the market compare.
- How it worksWhat it is and how it works in the body, in plain terms.
- Published studiesThe studies behind each use, popular claims checked against them, and trials still under way.
- Word of mouthWhat patients and practitioners report online, kept separate from the clinical evidence.
- Clinical perspectiveA closing read of where the evidence is solid, where it is thin, and what has not been studied.
Sources
- 1Chronic consumption of an inositol-enriched carob extract improves postprandial glycaemia and insulin sensitivity in healthy subjects: A randomized controlled trial.pubmed.ncbi.nlm.nih.govBañuls, Rovira-Llopis, Falcón et al. · Clinical nutrition (Edinburgh, Scotland) · 2016 · Pubmed
- 2Evaluation of Commercial Carob Syrups (Ceratonia siliqua L.) in Randomized Controlled Trials: Effects on Lipid, Glycaemic, and Anthropometric Parameters.pubmed.ncbi.nlm.nih.govPlanes-Muñoz, MLÁ, Frontela-Saseta et al. · Foods (Basel, Switzerland) · 2025 · Pubmed
- 3Effects of Specific Carob (Ceratonia siliqua L.) Liquid Concentrate on Glucose Metabolism in Subjects with Prediabetes: A Randomized Double-Blind Controlled Clinical Trial.pubmed.ncbi.nlm.nih.govPérez-Piñero, Muñoz-Carrillo, Herrera-Fernández et al. · Nutrients · 2026 · Pubmed
- 4Effects of carob (Ceratonia siliqua) and carob-derived products on glycaemic control and insulin resistance: A systematic review of clinical trials.pubmed.ncbi.nlm.nih.govVictoria-Montesinos, González-Louzao, Barcina-Pérez et al. · Nutrition research (New York, N.Y.) · 2026 · Pubmed
- 5Effects of Ganoderma lucidum and Ceratonia siliqua on blood glucose, lipid profile, and body composition in women with fibromyalgia.pubmed.ncbi.nlm.nih.govPazzi, Adsuar, Domínguez-Muñoz et al. · Nutricion hospitalaria · 2021 · Pubmed
- 6A clinical trial about effects of prebiotic and probiotic supplementation on weight loss, psychological profile and metabolic parameters in obese subjects.pubmed.ncbi.nlm.nih.govBen Othman, Ben Amor, Mahjoub et al. · Endocrinology, diabetes & metabolism · 2023 · Pubmed
- 7Fenugreek Is Superior to Guar Gum, Locust Bean Gum and Tara Gum for Metabolic Health: A Systematic Review.pubmed.ncbi.nlm.nih.govJuhász, Kara, É et al. · Nutrients · 2026 · Pubmed
- 8Carob pulp preparation rich in insoluble fibre lowers total and LDL cholesterol in hypercholesterolemic patients.pubmed.ncbi.nlm.nih.govZunft, Lüder, Harde et al. · European journal of nutrition · 2003 · Pubmed
- 9Tannin-rich carob pod for the treatment of acute-onset diarrhea.pubmed.ncbi.nlm.nih.govLoeb, Vandenplas, Würsch et al. · Journal of pediatric gastroenterology and nutrition · 1989 · Pubmed
- 10Herbal Medicines for Gastrointestinal Disorders in Children and Adolescents: A Systematic Review.pubmed.ncbi.nlm.nih.govAnheyer, Frawley, Koch et al. · Pediatrics · 2017 · Pubmed
- 11The Effect of Ceratonia siliqua (Carob) on Male Infertility: A Systematic Review and Meta-analysis of invitro and randomized controlled trials.pubmed.ncbi.nlm.nih.govAlibabaei-Omran, Delavar, Moher et al. · JBRA assisted reproduction · 2026 · Pubmed
- 12The Effect of Carob (Ceratonia Siliqua) on Sperm Parameters of Infertile Men: Systematic Review and Meta-Analysis of Randomized Controlled Trials.pubmed.ncbi.nlm.nih.govKaraahmet, Gençtürk, Kınık · Reproductive sciences (Thousand Oaks, Calif.) · 2024 · Pubmed
- 13A systematic review of nonpharmacological and nonsurgical therapies for gastroesophageal reflux in infants.pubmed.ncbi.nlm.nih.govCarroll, Garrison, Christakis · Archives of pediatrics & adolescent medicine · 2002 · Pubmed
- 14Cisapride treatment for gastro-oesophageal reflux in children.pubmed.ncbi.nlm.nih.govMaclennan, Augood, Cash-Gibson et al. · The Cochrane database of systematic reviews · 2010 · Pubmed
- 15Use of a new thickened formula for treatment of symptomatic gastrooesophageal reflux in infants.pubmed.ncbi.nlm.nih.govBorrelli, Salvia, Campanozzi et al. · Italian journal of gastroenterology and hepatology · 1997 · Pubmed
- 16US product labelsdsld.od.nih.govWarnings printed on US dietary supplement labels with this ingredient, from the NIH Office of Dietary Supplements' Dietary Supplement Label Database (DSLD). Manufacturers' precautions, not evidence of harm
- 17Functional polysaccharides of carob fruit: a review.pubmed.ncbi.nlm.nih.govZhu, Zayed, Zhu et al. · Chinese medicine · 2019 · Pubmed
- 18Carob is not allergenic in peanut-allergic subjects.pubmed.ncbi.nlm.nih.govFiocchi, Restani, Travaini et al. · Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 1999 · Pubmed