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Ingredients

Butcher's Broom

Ruscus aculeatus

Snapshot

IndicationsContraindications
  • Chronic venous insufficiency1, 2
  • Leg heaviness and pain1
  • Leg edema1, 2
  • Venous disease quality of life3, 4
  • Secondary arm lymphedema5
  • Hemorrhoid symptoms6
  • Hypersensitivity to Ruscus6
  • Pregnancy and lactation7

Butcher's broom (Ruscus aculeatus) is a Mediterranean shrub whose rhizome and root contain steroidal saponins, chiefly ruscogenin, along with flavonoids8. Extracts act on veins, capillaries, and lymphatics and carry anti-inflammatory properties9. That venous and lymphatic tone effect drives its use for leg heaviness, swelling, and pain in chronic venous insufficiency, and, in a combination product, for arm lymphedema after breast cancer treatment. Traditional use also covers itching and burning from hemorrhoids6. Trial populations are mostly women with long-standing venous disease2.

A meta-analysis of randomized placebo-controlled trials found Ruscus-containing products improved leg symptoms and reduced edema versus placebo1. A placebo-controlled trial of Ruscus extract alone in women with chronic venous insufficiency reduced leg volume over three months2. Much of the clinical literature tests fixed combinations with hesperidin methyl chalcone and vitamin C, which limits attribution to Ruscus alone8. In 2026, a pharmacovigilance disproportionality analysis of Food and Drug Administration (FDA) adverse event reports flagged butcher's broom for kidney-related events; no trial has tested this signal. Products are sold as capsules and liquid extracts; see Form comparison.

Per the European Medicines Agency herbal monograph, patients with sudden leg swelling, skin ulcers, or cardiac or renal insufficiency are directed to a doctor before use for venous symptoms6.

Last updated October 17, 2026. Read how we make monographs.

In the full monograph

35 sources, 28 studies

  • When to useThe situations practitioners use it for, each with the reason and the study behind it.
  • SafetyWho should avoid it, who needs extra care, and the side effects reported in studies.
  • Protocol notesThe doses used in studies, how and when they were taken, and how the forms on the market compare.
  • How it worksWhat it is and how it works in the body, in plain terms.
  • Published studiesThe studies behind each use, popular claims checked against them, and trials still under way.
  • Word of mouthWhat patients and practitioners report online, kept separate from the clinical evidence.
  • Clinical perspectiveA closing read of where the evidence is solid, where it is thin, and what has not been studied.

Sources

  1. 1Efficacy of Ruscus extract, HMC and vitamin C, constituents of Cyclo 3 fort®, on improving individual venous symptoms and edema: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials.pubmed.ncbi.nlm.nih.govKakkos, Allaert · International angiology : a journal of the International Union of Angiology · 2017 · Pubmed
  2. 2Efficacy and safety of a Butcher's broom preparation (Ruscus aculeatus L. extract) compared to placebo in patients suffering from chronic venous insufficiency.pubmed.ncbi.nlm.nih.govVanscheidt, Jost, Wolna et al. · Arzneimittel-Forschung · 2002 · Pubmed
  3. 3Assessment of quality of life in Mexican patients suffering from chronic venous disorder - impact of oral Ruscus aculeatus-hesperidin-methyl-chalcone-ascorbic acid treatment - 'QUALITY Study'.pubmed.ncbi.nlm.nih.govGuex, Enriquez Vega, Avril et al. · Phlebology · 2009 · Pubmed
  4. 4Quality of life improvement in Latin American patients suffering from chronic venous disorder using a combination of Ruscus aculeatus and hesperidin methyl-chalcone and ascorbic acid (quality study).pubmed.ncbi.nlm.nih.govGuex, Avril, Enrici et al. · International angiology : a journal of the International Union of Angiology · 2010 · Pubmed
  5. 5Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT.pubmed.ncbi.nlm.nih.govCluzan, Alliot, Ghabboun et al. · Lymphology · 1996 · Pubmed
  6. 6EMAema.europa.euEuropean Medicines Agency — European Union herbal monograph from the Committee on Herbal Medicinal Products (HMPC)
  7. 7US product labelsdsld.od.nih.govWarnings printed on US dietary supplement labels with this ingredient, from the NIH Office of Dietary Supplements' Dietary Supplement Label Database (DSLD). Manufacturers' precautions, not evidence of harm
  8. 8Current Insights into the Phytochemistry and Pharmacological Properties of Ruscus aculeatus.pubmed.ncbi.nlm.nih.govPacuła, Sowa, Feldo et al. · Molecules (Basel, Switzerland) · 2025 · Pubmed
  9. 9The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease.pubmed.ncbi.nlm.nih.govJawien, Bouskela, Allaert et al. · International angiology : a journal of the International Union of Angiology · 2017 · Pubmed